Severe life threatening asthma

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Risk of severe life threatening asthma.

There have been many components to the debate on the safety of 12 agonists but one of the most important has been the interpretation of the New Zealand studies investigating associations between asthma death and the use of the inhaled P2 agonist fenoterol. In 1976 a striking rise in the death rate from asthma occurred in New Zealand' and many studies have been performed to try and unravel the c...

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Demographic characteristics of patients with severe life threatening asthma: comparison with asthma deaths.

BACKGROUND Studies of mortality from asthma have suggested that a very severe asthma attack identifies a group at greatly increased risk of subsequent death from the disease. This study compares the demographic characteristics of asthmatic patients who required management in an intensive care unit for a severe life threatening attack between 1981 and 1987 with a group who died of asthma between...

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Acute asthma and the life threatening episode.

OBJECTIVE To present a clinical approach to the management of acute asthma and the life threatening episode of asthma. DATA SOURCES A review of published peer-review articles and studies reported from 1966 to 1999 and identified through a MEDLINE search on the management of acute asthma, status asthmaticus and acute fulminant asthma. SUMMARY OF REVIEW Asthma is a disease caused by a chronic...

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Life-threatening asthma: pathophysiology and management.

Asthma prevalence and mortality have been increasing over the past 2 decades, despite advances in medical therapy. In 2003 the National Health Interview Survey reported over 4,000 asthma-related deaths. A small proportion of people with severe asthma use a large proportion of health-care resources and bear the burden of asthma-related morbidity and mortality. The management of acute asthma is c...

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Risk of severe life threatening asthma and beta agonist type: an example of confounding by severity.

BACKGROUND A study was undertaken to test the hypothesis that a particular inhaled beta agonist, fenoterol, increases the incidence of severe life threatening asthma. METHODS A retrospective cohort was assembled comprising 655 patients with asthma aged 15-55 years who attended a single Auckland hospital for acute asthma between 1 January 1986 and 31 December 1987 (the "index event"). Patients...

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ژورنال

عنوان ژورنال: Thorax

سال: 2001

ISSN: 0040-6376

DOI: 10.1136/thorax.56.11.897b